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Valentine.gr  

May 2018

Did you know that the ornamental but highly poisonous plant Digitalis purpurea is used as a medication for heart failure?

Foxglove (Digitalis purpurea).

Foxglove - Digitalis purpurea

Digitalis purpurea (foxglove, common foxglove, purple foxglove or lady's glove) is a species of flowering plant in the plantain family Plantaginaceae, native to and widespread throughout most of temperate Europe. It is also naturalised in parts of North America and some other temperate regions. The plants are well known as the original source of the heart medicine digoxin (also called digitalis or digitalin).

Digitalis purpurea is an herbaceous biennial or short-lived perennial plant. The leaves are spirally arranged, simple, 10–35 cm (3.9–13.8 in) long and 5–12 cm (2–5 in) broad, and are covered with gray-white pubescent and glandular hairs, imparting a woolly texture. The foliage forms a tight rosette at ground level in the first year.

The flowering stem develops in the second year, typically 1–2 m (3.3–6.6 ft) tall, sometimes longer. The flowers are arranged in a showy, terminal, elongated cluster, and each flower is tubular and pendent. The flowers are typically purple, but some plants, especially those under cultivation, may be pink, rose, yellow, or white. The inside surface of the flower tube is heavily spotted. The flowering period is early summer, sometimes with additional flower stems developing later in the season. The plant is frequented by bees, which climb right inside the flower tube to gain the nectar within.

The fruit is a capsule which splits open at maturity to release the numerous tiny 0.1-0.2 mm seeds.

The plant is popular as a garden subject, and numerous cultivars have been developed with a range of colours from white through pink to purple, such as "Dalmatian Purple". Cultivated forms often show flowers completely surrounding the central spike, in contrast to the wild form, where the flowers only appear on one side. D. purpurea is easily grown from seed or purchased as potted plants in the spring.

The Latin name, digitalis comes from the word digitanus, meaning finger for the thimble shaped flowers that look like you could fit your finger right inside.

Roman mythology associates the flower with Juno (Hera) who learned midwife lore from the Goddess Flora, including a supernatural method of using foxgloves to induce parthenogenetic (single-sex) pregnancy. Flora placed a foxglove blossom on her thumb, touched Juno on the tips of her breasts & on her belly, so that she became impregnated with Mars who had no father.

No matter what its name or legend, the plant is highly poisonous and, in the right dosage, has the ability to severely affect the heart rate, possibly causing death. Due to the presence of the cardiac glycoside digitoxin, the leaves, flowers and seeds of this plant are all poisonous to humans and some animals and can be fatal if ingested. Symptoms of Digitalis poisoning include a low pulse rate, nausea, vomiting, and uncoordinated contractions of different parts of the heart, leading to cardiac arrest and finally death.

Although foxglove is very dangerous if misused, it has a long history of medicinal use for heart and kidney problems, edema and aconite poisoning.

Extracted from the leaves, this same compound, which is considered the beginning of modern therapeutics, whose clinical use was pioneered  in 1785 by William Withering, is used as a medication for heart failure. He recognized it "reduced dropsy", increased urine flow and had a powerful effect on the heart. Unlike the purified pharmacological forms, extracts of this plant did not frequently cause intoxication because they induced nausea and vomiting within minutes of ingestion, preventing the patient from consuming more.

Legend says that Van Gogh used it to treat his epilepsy.One of the interesting stories in the history of digoxin is the link with Vincent Van Gogh. Much has been written about the physical and mental health problems that Van Gogh had in his life and numerous diagnoses have been proposed. Among these diagnoses is the suspicion that he suffered from digitalis (foxglove) toxicity, which resulted in the frequent use of yellow halos in his paintings due to xanthopsia. Supporting this hypothesis is the fact that when Vincent painted his personal physician in the Portrait of Doctor Gachet he was holding the foxglove plant.

An old saying about foxglove goes "It can raise the dead and it can kill the living.


Source:

https://en.wikipedia.org/wiki/Digitalis_purpurea
https://theresagreen.me/2012/06/20/foxglove-fairytales-myths-medicine/
http://www.witchipedia.com/herb:foxglove
http://theconversation.com/weekly-dose-digoxin-the-heart-medicine
-that-may-have-given-us-van-goghs-starry-night-57980

 

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Abyssinian banana - Ensete ventricosum
Goldenrain Tree - Koelreuteria paniculata
Naranjilla - Lulo - Solanum quitoense
Brazil nut tree - Bertholletia excelsa
Sea grape - Coccoloba uvifera
Bignay - Antidesma bunius
Cashew - Anacardium occidentale
Giant Himalayan Lily - Cardiocrinum giganteum
African Hemp - Sparrmannia africana
Lychee - Litchi chinensis
Prickly Heath - Gaultheria mucronata
Hoodia - Bushman's hat - Hoodia gordonii
Cannibals Tomato - Solanum viride
Ashoka - Saraca asoca
Ackee - Blighia sapida
African plum - Safou - Dacryodes edulis
Solandra - Solandra maxima
Stapelia - Stapelia gigantea
Foxglove - Digitalis purpurea
Swiss Cheese Plant - Monstera deliciosa
Chocolate flower - Berlandiera lyrata
Sandersonia - Sandersonia aurantiaca
Northern Japanese Magnolia - Magnolia kobus
Champak - Magnolia champaca
Hooker’s lips - Psychotria elata
Suicide Tree - Cerbera odollam
Konjac - Amorphophallus konjac
Madagascar ocotillo - Alluaudia procera
Water Banana - Typhonodorum lindleyanum
Salak - Salacca zalacca
Natal Plum - Carissa macrocarpa
Ashanti blood - Mussaenda erythrophylla
Duranta - Duranta erecta
Maqui - Aristotelia chilensis
Manuka - New Zealand Tea Tree - Leptospermum scoparium
Suriname cherry - Eugenia uniflora
Australian Finger Lime - Citrus australasica
Sacred Flower of the Incas - Cantua buxifolia
Job's tears - Coix Lacryma-jobi
Velvet Bean - Mucuna pruriens
Java Apple - Syzygium samarangense
Screwpine - Pandanus utilis
Marimo - Aegagropila linnaei
Achocha/Caigua - Inca cucumber - Cyclanthera pedata
Rubber Tree - Hevea brasiliensis
Sugar cane - Saccharum officinarum
Sacha inchi - Plukenetia volubilis
Coffea - Coffee Tree - Coffea arabica
Liquorice - Licorice - Glycyrrhiza glabra
Mullein -Verbascum thapsus
Iceplant - Mesembryanthemum crystallinum
Chayote - Sechium edule
Roselle - Hibiscus sabdariffa
Black Goji - Lycium ruthenicum Murray
Rose Cactus - Pereskia grandifolia
Durian - Durio zibethinus
Jackfruit tree - Artocarpus heterophyllus
Cassabanana - Sicana odorifera
Chilean myrtle - Arrayan - Luma apiculata
Kurrajong - Brachychiton populneus
Rice-paper Plant -Tetrapanax papyrifer
Shell Ginger - Alpinia zerumbet
Harlequin Glorybower - Clerodendrum trichotomum
Coco de Mer - Lodoicea maldivica
Silver Tree - Leucadendron argenteum
Buffaloberry - Shepherdia argentea
Himalayan Honeysuckle - Leycesteria formosa
Raisin Tree - Hovenia dulcis
Borojo - Alibertia patinoi - Borojoa patinoi
Butterfly Pea - Clitoria ternatea
Honey Flower - Melianthus major
Ombu - Phytolacca dioica
Lion's Ear - Wild Dagga - Leonotis leonurus
Moringa - Miracle Tree - Moringa oleifera
Sea Daffodil - Pancratium maritimum
Spear Lily - Gymea - Doryanthes
Camphor tree - Cinnamomum camphora
Waterwheel - Aldrovanda vesiculosa
Flowering rush - Butomus umbellatus
Four o'clock - Marvel of Peru - Mirabilis jalapa
Dead Man’s Fingers - Decaisnea
Bitter Melon - Momordica charantia
Shoapnuts Tree - Shoapberry - Sapindus
Acerola - Malpighia
Monkey Ladder - Sea Heart - Entada gigas
Cherimoya - Annona cherimola
Caper - Capparis spinosa
Lithops - Living Stones
Chaste Tree - Vitex agnus-castus
Chilean Lantern Tree - Crinodendron hookerianum
Parrot's Beak - Lotus berthelotii
Water Hyacinth - Eichhornia crassipes
Guaiac Tree - Guaiacum officinale - Lignum-vitae
Mickey Mouse bush - Ochna serrulata
Cow's Udder - Solanum mammosum
Miracle fruit - Synsepalum dulcificum
Akebia - Akebia quinata
Chilean Firebush - Embothrium coccineum
Caesalpinia - Caesalpinia pulcherrima
Welwitschia - Welwitschia mirabilis
Saguaro - Carnegiea gigantea
Schisandra - Schisandra chinensis
Monarda - Bee balm - Bergamot
Tamarind - Tamarindus indica
Neomarica - Walking Iris
Red hot poker - Kniphofia - Tritoma
Sikkim rhubarb - Rheum nobile
Reseda - Mignonette
Paulownia - Paulownia tomentosa
Belamcanda chinensis - Leopard lily
Blue Poppy - Meconopsis
Cannonball Tree - Couroupita guianensis
Tamarillo - Cyphomandra betacea
Goji - Wolfberry - Lycium barbarum
Vanilla - Vanilla Planifolia
Stevia - Stevia rebaudiana
Pachypodium
Physalis
Ceropegia
Sturt pea - Swainsona formosa
Clematis
Grevillea
Jade vine - Strongylodon macrobotrys
Sansevieria - Snake Plant
Trochetia
Yareta - Azorella compacta
African tulip tree - Spathodea campanulata
Angel's Trumpets - Brugmansia
Achiote - Annato - Bixa orellana
Sausage Tree - Kigelia pinnata
Castor Oil Plant - Ricinus communis
Firewheel Tree - Stenocarpus sinuatus
Bat Flower - Tacca
Snake gourd - Trichosanthes cucumerina
Sedum
Hydnora - Hydnora africana
Pickerel Weed - Pontederia
Argan - Argania spinosa
Astilbe - False Goats Beard
Feijoa - Pineapple Guava - Acca sellowiana
Aquilegia - Columbine
Cassiope
Sweet Box - Sarcococca
Christmas Cactus - Schlumbergera
Foxtail Lily - Eremurus
Rue - Ruta graveolens
Pittosporum
Ylang-Ylang - Cananga odorata
Rose of Jericho - Anastatica hierochuntica
Gunnera
Waterlily - Nymphaea
Calico Flower - Aristolochia
Daylily - Hemerocallis
Contorted hazel - Corylus avellana Contorta
Torch Ginger - Etlingera elatior
Mistletoe - Viscum album
Devil´s claw - Harpagophytum procumbens
Teasel - Dipsacus
Pampas grass - Gynerium argenteum - Cortaderia Selloanna
Purple coneflower - Echinacea purpurea
Coral Tree - Erythrina crista-galli
Portulaca
Lobelia
Field Poppy - Papaver Rhoeas
Narcissus - Daffodil
Mimosa pudica - Sensitive Plant
Boxwood - Buxus sempervirens
Firethorn - Pyracantha
Star of Bethlehem - Ornithogalum
Cosmos
Muscari - Grape Hyacinth
Papyrus - Cyperus papyrus
Zinnia
Honeysuckle - Lonicera
Passiflora - Passion Flower
Calendula - Marigold
Lupine - Lupinus
Canna - Indian Shot
Witch Hazel - Hamamelis
Oak - Quercus
Brunsvigia - Candelabra Flower
Tree peony - Paeonia suffruticosa
Olive - Olea europaea
Cornflower - Centaurea cyanus
Desert rose - Adenium obesum
Oleander - Nerium Oleander
Abutilon
Sweet Pea - Lathyrus odoratus
Chaenomeles - Flowering Quince
Forsythia
Amaryllis - Hippeastrum
Butchers broom - Ruscus aculeatus
Bay Laurel - Laurus nobilis
Gloriosa
Bamboo
Gladiolus
Artichoke - Cynara scolymus
Clivia - Clivia Miniata
Dipladenia - Dipladenia sanderii
Date palm - Phoenix dactylifera
Peach - Prunus persica
Almond - Prunus amygdalus
Willow - Salix
Pomegranate - Punica granatum
Protea cynaroides
Colchicum autumnale
Bird of Paradise - Strelitzia reginae
Cardon - Pachycereus pringlei
Wolffia arrhiza
Puya raimondii
Fuchsia
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Primula - Primerose
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Edelweiss - Leontopodium alpinum
Helleborus Niger - Christmas Rose
Zantedeschia - Calla Lily
Fritillaria imperialis - Crown imperial
Aster
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Common Sunflower - Helianthus annuus
Bee Orchid - Orphys apifera
Convalaria majalis - Lily of the Valley - Muguet
Syringa Vurgaris - Lilac
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Snowdrop - Galanthus
Poinsettia - Euphorbia pulcherrima
Dionaea muscipula
Banksia
Sea anemone
Amorrhophallus titanum
Rafflesia arnoldi

 

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